Studies on the Metabolic Fate of Sodium Hyaluronate (SL-1010) after Intra-articular Administration. (I). Distribution, Metabolism and Excretion after Intra-articular Injection into Rabbit Knee.
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چکیده
منابع مشابه
Intra-articular Duration of Durolane™ after Single Injection into the Rabbit Knee
OBJECTIVE The aim of the present study was to investigate the intra-articular duration of Durolane™ in a rabbit model to allow comparison between Durolane™ residence time and data reported for other hyaluronic acid products as well as native hyaluronic acid. DESIGN (14)C-labeled Durolane™ was manufactured by labeling the cross-linker used for stabilization. A single injection of approximately...
متن کاملIntra-articular Injections of Sodium Hyaluronate (Hyalgan
1 Department of Sports Medicine, College of Health Care, China Medical University and University Hospital, Taichung 404, Taiwan. 2 Department of Medicine, Division of Rheumatology, Immunology, Allergy, Taipei Medical University Hospital, Taipei, Taiwan 3 Department of Orthropaedic, Taipei Medical University Hospital, Taipei, Taiwan 4 Department of Physical Medicine and Rehabilitation, Taipei Me...
متن کاملOutcomes of intra-articular injection of sodium hyaluronate for the treatment of osteoarthritis of the knee.
BACKGROUND Intra-articular injection of hyaluronic acid has become an intervention step between conservative and operative treatment of knee osteoarthritis. This is recommended by the American College of Rheumatology (ACR) and the European League Against Rheumatism (EULAR). However, the expected outcomes and the selection criteria are undetermined and controversial. A few articles have mentione...
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Background and Aims: Knee arthroscopy is used to diagnose and treat intra-articular lesions. The control of acute pain after arthroscopy requires the use of a method with the least side effects and most efficacies. This study aimed to compare the sedative effect of bupivacaine in combination with morphine, methylprednisolone, or alone in knee arthroscopy after intra-articular injection. Materi...
متن کاملIntra-articular injection of hyaluronate versus corticosteroid in adhesive capsulitis.
The goal of this study was to prospectively compare the early clinical results of intra-articular injection of hyaluronate or corticosteroid in patients with idiopathic adhesive capsulitis. The authors' hypothesis was that there would be no difference between groups. Sixty-eight patients with idiopathic adhesive capsulitis were equally randomized to receive either corticosteroid or hyaluronate ...
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ژورنال
عنوان ژورنال: Drug Metabolism and Pharmacokinetics
سال: 1993
ISSN: 0916-1139
DOI: 10.2133/dmpk.8.333